Symptoms And Diagnosis Of Alzheimer s Disease - 2581 Words

Word Count: 1840 It is estimated that currently 5.1 million Americans may have Alzheimer’s disease. [1] 60-70% of dementia cases in the elderly are caused by Alzheimer’s. [2] As the population ages a greater percentage of Americans will be impacted whereas between present time and 2050 it is estimated that 20 percent of the population will be in an age category that puts them at risk. [1] The disease is a progressive, degenerative disorder that attacks the neurons resulting in memory loss, language skills, thinking and behavioral changes. Diagnostic and therapeutic approaches to this disease are changing due to knowledge that the underlying pathology begins 10-20 years before the symptoms appear. [3] Therefore new methods are†¦show more content†¦[5] In an Alzheimer’s Dementia brain the insoluble Aï  ¢ exceeds soluble forms of Aï  ¢ by a factor of about 100-fold. [6] It has been indicated that these plaques can be cleared. [7] Plaques are composed of insoluble Aï  ¢ peptides, mostly 42 amino acids in length (Aï  ¢-42) [8] Knowledge of the initial deposition of Aï  ¢ plaques is important to improve understanding of early Alzheimer’s Dementia pathology. It is suggested that APP mismetabolism and subsequent Aï  ¢ aggregation are the primary events driving pathogenesis. [9] Mutations in the Aï  ¢ precursor protein gene on chromosome 21, lying in or near the Aï  ¢Ã¯â‚¬  peptide region, cause early-onset, autosomal dominant familial forms of Alzheimer’s Dementia. [10] The deposition of Aï  ¢ is likely important for signifying the beginning of the pathological cascade even if it may not be the only or main causal event. However, since all young healthy persons and many older individuals (who do not have Alzheimer’s Dementia) have no evidence of Aï  ¢ deposition the conversion of a non-demented individual with no evidence of Aï  ¢ plaques to Aï  ¢ deposits in a cerebral distribution suggests a pathological event. Biomarkers provide a unique, useful biological measure of the underlying pathology independent of any clinical signs and neuropsychological characteristics of Alzheimer’s Dementia. Identification of reliable biomarkers is critical

Got Milk Advertisement Analysis Essay - 1113 Words

â€Å" This advertisement was found in the October issue of Cosmopolitan. â€Å"Got Milk† advertisements are seen in all types of magazines from sports to beauty, featuring many different kinds of celebrities selling their product. The product being sold in â€Å"Got Milk† advertisements is, of course, milk. They are trying to reinforce that the calcium in milk keeps bones strong and helps prevent osteoporosis. In this advertisement for milk irony is it’s secret weapon to get the point across. There is a green eyed blonde with a low cut â€Å"little black dress† caressing her flawless body with her arm around a martini glass filled with milk. She is seductively leaning against a glass covered wooden bar with a luring gleam in her eyes. Her and the milk are†¦show more content†¦Therefore, the main focus of this advertisement is that the milk should be chosen over other temptations. It also implies that the empowerment of goodness will always prevail over badness. The proportions in the advertisement show the viewer that the larger, more prominent object, the milk, is the best decision and will do your body good. The positioning of the martini milk glass and the liquor bottles in this advertisement leads one to think about the good and bad choices they make for themselves everyday. The liquor bottles are faded in the background and carefully situated on the shelves of the bar to show temptation towards making a bad decision. Temptation is just what the advertiser want you to feel when viewing the advertisement. The purpose for the liquor bottles position is that things that are bad for you need to just fade into the background and the things that are good for you need to keep your focus. In the middle of the advertisement, the woman’s slender arm is wrapped around the martini milk glass, which is next to her sexy little black dress. The purpose of the position of the martini milk glass shows that the seductive looking woman has made her good/pure decision to choose to drink the milk over the liquor. With her decision, the viewer is being tempted by her green, seductive eyes to make the same good decision towards the milk. The martini glass is positioned in front of the faded liquor bottles in thisShow MoreRelatedGot Milk? Case Analysis824 Words   |  4 PagesBranding a Commodity: A Case Study Analysis of got milk? Samantha White-Hauser I. Introduction One will hardly ever find someone who has not seen the popular advertisements of famous actors, athletes, or musicians sporting a mustache adorned with got milk?. This campaign was an extremely recognizable, but marketers could have done more to make got milk? even more profitable. 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It established how a brand can be resurrected with a creative branding strategy. In order to revive the declining sales of milk this campaign was started for California Milk Processor Board and was carried out by Goodby, Silverstein and partners. TheRead MoreSteve Easterbrook s New Marketing Strategies1364 Words   |  6 Pageshow Steve Easterbrook’s new marketing strategies affected their sales. I will conduct a SWOT analysis and a marketing mix. The SWOT analysis will allow me to identify the benefits and flaws of the new marketing strategy. By mentioning the price, product, place, and promotion in the marketing mix, it will allow me to identify how effective the new marketing strategies have been. Evaluation: SWOT Analysis Strengths- McDonalds has the best brand equity in the world. As soon as a customer sees â€Å"GoldenRead MoreThe Corporation Film Analysis Essay1736 Words   |  7 PagesThe Corporation Film Analysis The Corporation was based on a book written by Joel Bakan. It is a documentary film that looks at the history of corporation and follows them up until present day to illustrate their dominance in society. I found this film very interesting with me once being part of the corporate world and finding my way onto another career path for many of the reasons illustrated in this film. This film had an underlying statement of corporations’ number one concern was profitRead MoreSWOT and Value Chain Analysis of McDonalds1401 Words   |  6 Pagesï » ¿ Case analysis On McDonalds Sadikchya Acharya Kings College International American University Babarmahal, Kathmandu MBA Capstone Prof. Dr. Raj Kumar Sharma International American University Kings College Babarmahal, Kathmandu Introduction and Background McDonalds as establishes in 1955 corporation and the multinational was first started by form Roy, it has its global operation for more than 119 countries selling its food items globally specially Korc. Currently as we see the data there areRead MoreMarketing Mix1477 Words   |  6 Pagesdepend on one mix always explore other avenues. The combining and coordination of these elements will be more effective than depending on one. The concept is simple. For instance, another common mix is a cake mix. Normally, all cakes contain eggs, milk, flour and sugar, but you can always modify the cake by changing the mix elements. So for a sweeter cake add more sugar! This example also applies to the marketing mix. The offer you make to you customer can be altered by varying the mix elements

Assisi Essay Example For Students

Assisi Essay Critical Evaluation-AssisiA poem that I have been studying recently is Assisi by Norman McCaig, which I found very interesting to read because it made a statement which relates to our world today even though the poem was wrote about thirty or forty years ago. The poem has lots of ideas including effective figures of speech, good choice of words, important images and irony. The statement that McCaig makes is, where ever there is great wealth it always exists along side great poverty. The poem is set in Assisi in Italy around the 1970s were all the rich tourists are coming in hundreds from all different countries far and wide to see the frescoes painted by Giotto in Assisis huge cathedral. McCaig mainly focuses on the dwarf outside of the three-tier cathedral built in honour of St. Francis. McCaig then proceeds to the priest guiding the tourists around the cathedral telling them the history of Giottos frescoes and how they individually teach people the goodness of God and the suffering of his son. McCaig uses effective littery techniques to describe the tourists and to describe the dwarf. He then goes on to explain that the tourists are not studying the frescoes and are just there to boast about being there. Then he goes on to tell of the dwarfs voice when he says Grazie for the money one of the tourists have given to him outside the cathedral. McCaig uses juxtaposition by situating the dwarf outside of the huge three tier cathedral. McCaig also refers to the dwarf as a ruined temple. By saying this he creates a huge contrast between the dwarf and the cathedral, he also uses irony to compare the dwarf to St. Francis were he says: Outside the three tiers of churches built in honour of St. Francis, brother of thepoor, talker with birds, over whomhe had the advantage of not being dead yet. This is saying that the dwarf had an advantage over one group of people, the dead. I think that it was a good idea to situate the dwarf outside the huge cathedral and create the image of a great, strong, beautifully designed building standing over a small, weak, deformed person. McCaig gives the reader a graphic description of the dwarf in both stanzas 1 and 3 where he uses many littery techniques to describe the dwarf. In stanza 1 he uses alliteration, simile and metaphor to give the reader a graphic view of the dwarfs deformed body: The dwarf with his hands on backwardssat, slumped like a half-filled sackon tiny twisted legs from whichsawdust might run. He uses alliteration to say things like, sat slumped and tiny twisted, these two pieces of text give a good view of the dwarfs way of sitting and his little weak legs. The simile used is, Slumped like a half-filled sack. This tells me that the dwarf had no strength to keep himself up straight and every time he sat down his back got closer to the ground. McCaig also uses a metaphor to tell you of the dwarfs legs, Tiny twisted legs from which sawdust might run. Here he is speaking about the dwarf as if he was an old teddy bear, he is saying that his legs are so worn out that sawdust might run from them, this is what happened to the teddy bears in the late 19th centaury, they were filled with sawdust and if they wore away the sawdust would run out. In stanza 3 McCaig called the dwarf a ruined temple., this gives the image of the dwarf who is battered and bruised and over the years he has begun to rot since no one has been looking after him. McCaig says this because the dwarf has been living around the huge cathedral for many years and is now wearing away. McCaig goes on to give more details of the dwarfs appearance:whose eyes,wept pus, whose back was higher than his head, whose lopsided mouthAll of these properties of the dwarf are very brutal, McCaig says this to make the reader feel pity for the dwarf but surprisingly McCaig goes on to tell how the dwarf had a voice as sweet as a childs: Said Grazie in a voice as sweet as a childs when she speaks to her mother. .u58165c95f71c5ac26f9b8b66d6631235 , .u58165c95f71c5ac26f9b8b66d6631235 .postImageUrl , .u58165c95f71c5ac26f9b8b66d6631235 .centered-text-area { min-height: 80px; position: relative; } .u58165c95f71c5ac26f9b8b66d6631235 , .u58165c95f71c5ac26f9b8b66d6631235:hover , .u58165c95f71c5ac26f9b8b66d6631235:visited , .u58165c95f71c5ac26f9b8b66d6631235:active { border:0!important; } .u58165c95f71c5ac26f9b8b66d6631235 .clearfix:after { content: ""; display: table; clear: both; } .u58165c95f71c5ac26f9b8b66d6631235 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u58165c95f71c5ac26f9b8b66d6631235:active , .u58165c95f71c5ac26f9b8b66d6631235:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u58165c95f71c5ac26f9b8b66d6631235 .centered-text-area { width: 100%; position: relative ; } .u58165c95f71c5ac26f9b8b66d6631235 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u58165c95f71c5ac26f9b8b66d6631235 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u58165c95f71c5ac26f9b8b66d6631235 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u58165c95f71c5ac26f9b8b66d6631235:hover .ctaButton { background-color: #34495E!important; } .u58165c95f71c5ac26f9b8b66d6631235 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u58165c95f71c5ac26f9b8b66d6631235 .u58165c95f71c5ac26f9b8b66d6631235-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u58165c95f71c5ac26f9b8b66d6631235:after { content: ""; display: block; clear: both; } READ: Profession for Women EssayI think McCaig does this to give the reader an element of surprise by giving the dwarf such a sweet voice when the reader would expect a rough, deep voice, McCaig uses very good figures of speech in these both stanzas describing the dwarf. In stanza 3 there is an extended metaphor comparing the tourists to hens:A rush of tourists, clucking contentedly, fluttered after him as he scattered the grain of the word. McCaig uses this metaphor to show that the tourists are rushing after the priest because he is spreading the word of God, he compares the tourists to hens who are following the farmer as if he is scattering grain. This also shows that the tourists did not pay much attention to Giottos frescoes which told stories of God. This leads to the tourists devaluing the life and work of Christ. I think that McCaig has made a very clear image of the tourists and that he makes very good use of the metaphor by extending it. Throughout the poem there is the use of irony and sarcasm, the first piece of irony used is in stanza 1 were he compared the three tier cathedral built in honour of St. Francis to the little deformed dwarf. The next piece of irony is in stanza 2 were McCaig tells us that the priest is spending his time guiding rich tourists round the cathedral showing of Giottos frescoes instead of spending time with the people who need it most. The next and last piece of irony I will highlight is in stanza 3 were the dwarf is sitting outside the cathedral which was built to friend the poor begging. This is a good littery technique used by McCaig were he compares the cathedral which was supposedly built for the poor to the poor dwarf who is begging to the rich tourists. McCaig then goes on to use sarcasm when he compares the dwarf to St. Francis and says: He had the advantage of not being dead yet. This is true but the dwarf has nothing to live for and would most probably want to be dead. I think tha t these two techniques which were used by McCaig were really useful in describing the scenes he is trying to show the reader of the poem. In stanza 3 McCaig gives the reader the one and only experience of the dwarfs voice, from the way McCaig has vividly described the dwarf you would expect him to have a rough, deep voice but it is not:Whose lopsided mouth said Grazie in a voice as sweet as a childs when she speaks to her mother or a birds when it spoke to St. Francis. Once again McCaig bring St. Francis into the poemby comparing one of the birds voice when it spoke to St. Francis to the dwarfs voice as he says Grazie. This shows that McCaig is a good writer because he can use so many littery techniques to create a poem of this class. I have chosen a poem and studied it carefully, identified the littery techniques used. I looked at such ideas as effective figures of speech, choice of words, important images, irony. I have also showed how the poet has made the social comment:Where ever there is great wealth it always exists along side great poverty. Words/ Pages : 2,094 / 24

Snowboarding And Safety Essays - Snowboarding, Snowboard, Boot

Snowboarding And Safety RIDING SMART ADVICE FOR SAFE SNOWBOARDING Preventing injuries will allow us to focus on fun, teamwork, and achieving individual goals. The most common injuries in snowboarding are to the wrist, shoulder, and head. Here are a few simple tips that I follow to reduce my risk of injury. Follow Your Responsibility Code. Wear a protective gear such as a helmet, wrist guards, padded shorts, etc. Use a leash. Check your own equipment regularly. Your boots should fit snugly, without heel lift. If your board, boots, or bindings dont feel right, have a professional help you before riding again. Warm up and down properly. Spend a few minutes gently stretching your calves, hamstrings, thigh muscles, hips, torso, back, neck, and arms. Hold each stretch gently for 30 seconds. Recognize when you need a rest most injuries occur after lunchtime when tiredness sets in. Wear adequate clothing, preferably in layers. Dont forget good quality goggles. When I fall, I try to keep my hands clenched in a fist, I try not to panic or tense up. Then, I get out of the way of traffic, and look all ways before entering a run, or after a stop. Dont be tempted to skip professional instruction bad habits learned early on are difficult to resolve later. Sports and Games